A Review on Anti-Cancer Activity of Benzopyrazole and Thiazolidine-4-One Nucleus

Authors

  • Babita Patial Assistant Professor, Department of Pharmaceutical Chemistry, School of Pharmacy, Career Point University, Himachal Pradesh, INDIA.
  • Anshul Chawla Vice-Principal, CT College of Pharmacy, Jalandhar, Punjab, INDIA.
  • Rajiv Sharma Department of Pharmaceutical Chemistry, University Institute of Pharmaceutical Sciences, Chandigarh University, Mohali, INDIA.
  • Rubeena Akhter Department of Pharmacy, School of Pharmacy, Career Point University, Himachal Pradesh, INDIA.
  • Priya Sharma Department of Pharmacy, School of Pharmacy, Career Point University, Himachal Pradesh, INDIA.
  • Saksham Department of Pharmacy, School of Pharmacy, Career Point University, Himachal Pradesh, INDIA.
  • Ritesh Kumar Department of Pharmacy, School of Pharmacy, Career Point University, Himachal Pradesh, INDIA.

Keywords:

Benzoxazole, Thiazolidin-4-ones, Anticancer drug, Isolated Natural Product

Abstract

The review covers recent information about antioxidant, anticancer, anti-inflammatory, analgesic, anticonvulsant, antidiabetic, antiparasitic, antimicrobial, antitubercular and antiviral properties of thiazolidin-4-ones. Additionally, the influence of different substituents in molecules on their biological activity was discussed in this paper. Thus, this study may help to optimize the structure of thiazolidin-4-one derivatives as more efficient drug agents. Presented information may be used as a practical hint for rational design of new small molecules with biological activity, especially among thiazolidin-4-ones. The anticancer drug research and development is taking place in the direction where the new entities are developed which are low in toxicity and are with improved activity. Benzoxazole and its derivative represent a very important class of heterocyclic compounds, which have a diverse therapeutic area. Recently, many active compounds synthesized are very effective; natural products isolated with benzoxazole moiety have also shown to be potent towards cancer.

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2022-06-22

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Babita Patial, Anshul Chawla, Rajiv Sharma, Rubeena Akhter, Priya Sharma, Saksham, & Ritesh Kumar. (2022). A Review on Anti-Cancer Activity of Benzopyrazole and Thiazolidine-4-One Nucleus. International Journal for Research in Applied Sciences and Biotechnology, 9(3), 166–174. Retrieved from https://www.ijrasb.com/index.php/ijrasb/article/view/399

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