Detection of the Active Compounds of the Hot Aqueous Extract of Cinnamomum cassia using FTIR Technology and Testing as Anti-bacterial and Antioxidant

  • Afnan I. Abdulwahab Department of Applied Science, University of Technology, IRAQ
Keywords: Antibacterial, Antioxidant, Resistant, Extract, Active Compounds


The results of the FTIR analysis of the hot aqueous extract of bark indicated that it contains many groups and active compounds, and the results of the bacterial tests conducted by digging and spreading method showed a high inhibitory activity of the hot aqueous extract of cinnamon against all pathogenic bacterial strains and at different concentrations. It was observed that the highest efficacy of the extract was against bacteria an inhibition diameter of 35 mm at concentration 800 mg/mL in Bacillus sp. while the bacterial strains were resistant to most of the antibiotics, in the study (Amoxicillin, Gentamycin, Ampicillin, Erythromycin, Tetracycline) except for gentamicin, which showed inhibition of bacteria Staphylococcus aureus with a diameter 19mm and Serratia sp. in diameter17mm. We conclude from the study that the cinnamon plant contains many active compounds and that the hot aqueous extract of Cinnamomum cassia (cinnamon) bark has a high inhibitory ability for different bacterial strains, which exceeded the inhibitory ability of antibiotics.


Download data is not yet available.


Chandra, H.; Bishnoi, P.; Yadav, A.; Patni, B.; Mishra, A.P.; Nautiyal, A.R. Antimicrobial Resistance and the Alternative Resources with Special Emphasis on Plant-Based Antimicrobials—A Review. Plants 2017, 6, 16. [CrossRef] [PubMed]

David, B.; Wolfender, J.-L.; Dias, D.A. The pharmaceutical industry and natural products: Historical status and new trends. Phytochem Rev. 2015, 14, 299–315. [CrossRef]

Pye, C.R.; Bertin, M.J.; Lokey, R.S.; Gerwick, W.H.; Linington, R.G. Retrospective analysis of natural products provides insights for future discovery trends. Proc. Natl. Acad. Sci. USA 2017, 114, 5601–5606. [CrossRef]

Raghad K. Maeah , Butheina A. Hasoon , Afnan I.Alwahab, Khalida F. F. AL-azawi, Wafaa Beed Allah Hameedi .2020. Biosynthesis of silver nanoparticles using Hibiscus sabdariffa and their biological application .Eurasia J Biosci 14, 3377-3383 .

Afnan I. Abdulwahab, Butheina A. Hasoon, Raghad K.Maeah and Khalida F. Al-azaw. 2021.Preparation of Mentha Crispata Extract and Detection of its Biological Application. Sys Rev Pharm ,12(1):1151-1155

Butheina A. Hasoon, Afnan I. Abdulwahab,, Raghad Khwater Maeh, Khalida F. Al-azawi.: Preparation and Characterization of Silver Nanoparticle by Cordia myxa Extract and their Study Anticancer, Antioxidant, Antibacterial Activity Indian Journal of Forensic Medicine & Toxicology, July-September 2021, Vol. 15, No. 3

Shen Q, Chen F, Luo J:Comparison studies on chemical constituents ofessential oil from ramulus cinnamomi and cortex cinnamomi by GC-MS.Zhong Yao Cai2002,25:257–258.

Gruenwald J, Freder J, Armbruester N: Cinnamon and health. Crit Rev FoodSci Nutr2010,50:822–834.

Gharaiben N., Elayan and Salhab,A.(1988).Hypoglycemic effect of Teucrium olium Ethnopharmacol,24(1):93-99.

Silverstein, R. M., Webster, F. X. and Klemle, J .D.(2005). Sectrometic identification organic compounds.John Wiley &Sonc, Incl ̸ New Yorc.

Pepeljnjak, S., Kosalec, I., Kalođera, Z., & BLAŽEVIĆ, N. (2005). Antimicrobial activity of juniper berry essential oil (Juniperus communis L., Cupressaceae). Acta pharmaceutica, 55(4), 417-422.

Mishra N, Upma K, Shukla D (2000), Antifungal activity of essential oil of Cinnamomum zeylanicum. J Essent Oil Res 3, 97–110. Mothana RA, Lindequist U (2005), Antimicrobial activity of some medicinal plants of the island Soqotra. J Ethnopharmacol 96, 177–181.

Melvin Joe, M., Jayachitra J. and Vijayapriya M., ( 2009 ). Antimicrobial activity of some common spices against certain human pathogens . Journal of Medicinal Plants Research Vol. 3(11), pp. 1134-1136 .

Karada ˘glıo ˘glu, Ö.˙I.; Ulusoy, N.; Ba¸ser, K.H.C.; Hano ˘glu, A.; ¸Sık, ˙I. Antibacterial activities of herbal toothpastes combined with essential oils against Streptococcus mutans. Pathogens 2019, 8, 20. CrossRef]

Chaudhari, L.K.; Jawale, B.A.; Sharma, S.; Sharma, H.; Kumar, C.D.; Kulkarni, P.A. Antimicrobial activity of commercially available essential oils against Streptococcus mutans. J. Contemp. Dent. Pract. 2012, 13, 71–74.[CrossRef]

Abbaszadegan, A.; Dadolahi, S.; Gholami, A.; Moein, M.R.; Hamedani, S.; Ghasemi, Y.; Abbott, P.V.; Patil, S.Antimicrobial and cytotoxic activity of Cinnamomum zeylanicum, Calcium hydroxide, and triple antibiotic paste as root canal dressing materials. J. Contemp. Dent. Pract. 2016, 17, 105–113. [CrossRef]

Khuzaie R.F., Rashan J., and Al-Dori N., 1999, In Vitracts of some local Medicinal plants growing in Jordan ,J. J. Appli. Sci, 1(1) : 46-52

Allan G. , Robert A. , Denis St. J. Michael J. S. and James S. 1999,"An illustrated colour text clinical biochemistry ,ed. 2ed ,UK, p.106 -114

Bakken J.S.,Sander C.C.andThomson K.S., 1987.Selective ceftazidime resistance in E.coli association with changes in outer protein .J.Inf.Dis.155:1220-1225.

How to Cite
Abdulwahab, A. I. (2021). Detection of the Active Compounds of the Hot Aqueous Extract of Cinnamomum cassia using FTIR Technology and Testing as Anti-bacterial and Antioxidant. International Journal for Research in Applied Sciences and Biotechnology, 8(6), 95-101.