Detection about the Anti-Inflammatory Effect in Alcoholic Extract of Alhagi maurorum in vitro
This study was conducted to detect the presence of some active compounds in the extract of Alhagi maurorum plant, which was extracted by soxhlet using methanol as a solvent. The chemical survey showed the presence of glycosides, tannins, alkaloids and phenolic in the studied plant.The anti-inflammatory activity of the plant extract had been studied in vitro by two methods , albumin denaturation inhibition test and hemolysis stimulated by heating test and results showed the effectiveness of the Alhagi maurorum plant extract with compared to standard medicine (Aspirin) and negative control groups.
Henson, P.M. (2005).Dampening inflammation. Nat Immunol. 6: 1179-81.
Stankov, S.V. ( 2012 ). Definition of Inflammation, Causes of Inflammation and Possible Anti-inflammatory Strategies. The Open Inflammation Journal. 5: 1-9.
Nathan, C. and Ding, A.(2010). Non resolving inflammation. Cell.140: 871–882.
Barnig, C. and Levy, B.D. (2015). Innate immunity is a key factor for the resolution of inflammation in asthma. European Respiratory Review. 24: 141-153.
Wallace, J.L. and Ferraz , J.G. ( 2010 ). New pharmacologic therapies in gastrointestinal disease. Gastroenterol Clin North Am. 39:709-720
Subramanian , R. ; White , C.J. ; Sternbergh , W.C III ; Ferguson ,D.L. and Gilchrist , I.C. ( 2003 ). Nonhealing wound resulting from a foreign-body reaction to a radial arterial sheath. Catheter Cardiovasc Interv. 59:205–206.
Kumar, S. ; Bajwa1, B.S. ; Kuldeep ,S. and Kalia ,A.N. ( 2013 ). Anti-Inflammatory Activity of Herbal Plants: A Review. IJAPBC. 2(2): 272 –281.
Agnihotri,S. ; Wakode, S. and Agnihotri, A. ( 2010).An overview on anti-inflammatoryproperties and chemo-profiles of plants used in traditional medicine.IJNPR.1(2): 150-167.
Shaikh,R.U. ; Pund, M. M. and Gacche, R.N. ( 2016 ). Evaluation of anti-inflammatory activity of selected medicinal plants used in Indian traditional medication system invitro as well as invivo. Journal of Traditional and Complementary Medicine. 6(4): 355-361
Motar ,A.A ; Hussein , R.A. and Abdulbary , M. ( 2017 ). Anti-inflammatory effect of turmeric plant ( Curcuma longa L. ) rhizomes and myrrh (Commiphora myrrha L.) gums and ginkgo Ginkgo biloba L.leaves ( tablets ) extracts. Kerbala Journal of Pharmaceutical Sciences.13:59-69.
Liu , P. ; Wen , J. ; Duan , L. ; Arslan , E. ; Ertuğrul , K. and Chang , Z. ( 2017 ). Hedysarum L. (Fabaceae: Hedysareae) Is Not Monophyletic –Evidence from Phylogenetic Analyses Based on Five Nuclear and Five Plastid Sequences. PLOS ONE journal. 1-14.
Shakiba , Y. ; Rezatofighi , S.E. ; Nejad , S.M.S. and Ardakan , M.R. ( 2016 ). Antiviral Activity of Alhagi maurorum Medik’s Methanolic Extract on Foot and Mouth Disease Virus (FMDV) in Cell Cultures. Jundishapur J Nat Pharm Prod. 11(3):1-5 .
Goncharov, M.Yu.; Yakovlev ,G.P. and Vitovskaya , G.A. ( 2001). Composition of polysaccharides from above-ground part of Alhagi maurorum Medic. Rastitel'nye Resursy.37:60-63.
Amani , A.S.A. , Maitland , D.J. and Soliman , G.A. ( 2006 ). Antiulcerogenic Activity of Alhagi maurorum. Pharmaceutical Biology. 44(4): 292–296.
Nedhal, A. ; Al-Douri, L. and Al-Essa, Y. ( 2010 ). A Survey of Plants Used in Iraqi Traditional Medicine" . Jordan Journal of Pharmaceutical Sciences, 3(2): 100-108.
Neamah , N.F. ( 2012 ). A Pharmacological Evaluation of Aqueous Extract of Alhagi maurorum. Global Journal of Pharmacology. 6(1): 41-46.
Harborne,J.B. (1984). Phytochemical methods ; A guide to modern techniques of plant analysis , 2nd ed. Chapman andHall, LONDON. pp 307.
Sakat , S.; Juvekar , A.R. and Gambhire , M.N. ( 2010). In vitro antioxidant and anti-inflammatory activity of methanol extract of Oxalis corniculata Linn. International Journal of Pharma and Pharmacological Sciences. 2(1):146-155.
Shinde, U.A.; Kulkarni, K.R.; Phadke, A.S.; Nair , A.M.; Dikshit , V. J.; Mungantiwar and Saraf, M.N.( 1999 ). Mast cell stabilizing and lipoxygenase inhibitory activity of Cedrus deodara (Roxb.) Loud. Wood Oil. Indian J Exp Biol. 37(3):258-261.
Manukumar, G.H.M. and Umesha, S. (2015). Assessment of membrane stabilizing activity from honey. An in-vitro approach. Acta Sci. Pol. Technol. Aliment. 14(1): 85–90.
Priya ,M.( 2001 ). Biochemical investigations on the stability of biological membranes. Ph.D. Thesis in Biochemistry. Department Of Marine Biology, Microbiology And Biochemistry. Cochin University Of Science And Technology. Chapter 8. pp 88 .
Chippada, S.C. ; Volluri, S.S. ; Bammidi , S.R. and Vangalapati , M. ( 2011 ). In vitro anti-inflammatory activity of methanolic extract of Centella asiatica by HRBC membrane stabilisation. Rasayan J. Chem.. 4(2): 457-460.
Leelaprakash , G. and Dass , S.M. ( 2011 ). In vitro anti-inflammatory activity of methanol extract of Enicostemma axillare. Int. J. Drug Dev. & Res. 3(3): 189-196.
Vadivu ,R. and Lakshmi K.S. (2008). In vitro and in vivo anti-inflammatory activity of leaves of Symplocos cochinchinensis (Lour) Moore ssp Laurina. BANGLADESH J Pharmacol. 3: 121-124.
Oyedapo , O.O. ; Akinpelu, B.A. ; Akinwunmi , K.F. ; Adeyinka , M.O. and Sipeolu , F.O. ( 2010 ). Red blood cell membrane stabilizing potentials of extracts of Lantana camara andits fractions. International Journal of Plant Physiology and Biochemistry. 2(4): 46-51.
Chandra, S. ; Chatterjee, P. ; Dey, P. and Bhattacharya , S. ( 2012 ). Evaluation of in vitro anti-inflammatory activity of coffee against the denaturation of protein. Asian Pacific Journal of Tropical Biomedicine. S178-S180
Copyright (c) 2018 International Journal for Research in Applied Sciences and Biotechnology
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.