Intra Vaginal Drug Delivery System (Novel Drug Delivery System)

  • Ankit Kumar College of Pharmacy-Agra, (Approved by AICTE New Delhi & PCI), Affiliated to Dr. APJ Abdul Kalam Technical University (Lucknow), INDIA
  • Sanjeev Kumar College of Pharmacy-Agra, (Approved by AICTE New Delhi & PCI), Affiliated to Dr. APJ Abdul Kalam Technical University (Lucknow), INDIA
Keywords: VDDS, LHRH, vaginal immunization, bioadhesion, HYAFF

Abstract

In case of intra-vaginal route of drug administration the dosage form is applied vaginally for the convenient release of the dosage form and for better therapeutic action of the medicament, it is usually used in HIV patients. many conditions that affect the  female reproductive tract, such as , sexually transmitted diseases, fungal & bacterial infections,  cancer and various pathogens such as virus (human immunodeficiency virus, HIV), bacteria (Gardnerella vaginalis), fungi (Candida spp.) or parasites (Trichomonas vaginalis). Systemically active drugs (contraceptive steroids) as well as locally active drugs (metronidazole Zidovudine, Lamivudine) can be effectively delivered for an extended period of time by the help of intra-vaginal  controlled release system. Continuous infusion of drugs through vaginal mucosa results in the reduced possibilities of Hepatic- gastrointestinal first-pass metabolism, gastric impatience of drugs and vacillation of dosing interval. Current study focus on the, use of various polymers which are used in hydrogels, these polymers provide bioadhesive property to the vaginal formulations, so that the vaginal formulation remains on vaginal tissues for 3- 4 days. Currently available vaginal dosage forms have several limitations, such as leakage and messiness necessitating the need to develop novel drug delivery systems.

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References

A Review on Vaginal Route as a Systemic Drug Delivery. Ashok. V, R. Manoj Kumar, D. Murali and Arkendu Chatterjee, Department of Pharmaceutics. Nalanda College of Pharmacy, Charlapally, Hyderabad Road, Nalgonda-508001, Andhra Pradesh, India

Intravaginal Drug Delivery System: Compherensive Approach to Vaginal Formulations. Patilprashant*, Bhopalepragati, Saudagarravindranathb 21 - 0975-1491. Journal of Drug Delivery and Therapeutics Open Access Topharmaceutical and Medical Research.

Studies And Methodologies On Vaginal Drug Permeation☆Ritamonteiro Machado A Ana Palmeira-De-Oliveira A,B, Carlos Gaspar A, Ba Cics: Ubi — Health Sciences Research Center, Faculty Of Health Sciences, University Of Beira Interior, Covilhã, Portugal

Review Article Vagina As An Application Site For Drug Delivery Anita Patel1*, Jayvadan Patel 1 Research Scholar, Bhagwant University, Ajmer, Rajsthan, India 2 Department Of Pharmaceutics, Nootan Pharmacy College, Visnagar, Gujarat, India

A Review Of Current Intravaginal Drug Delivery Approaches Employed For The Prophylaxis Of Hiv/Aids And Prevention Of Sexually Transmitted Infectionsvalencem. K. Ndesendo,1viness Pillay,1,4 Yahy

An Overview Of Intra-Vaginal Drug Delivery System Arkenduchatterjee*, Benoybratabhowmik And Lalit Kumar * Department Of Pharmaceutics, Himalayanpharmacy Institute, Majhitar, Rangpo, E.Sikkim-737136, Indiaforcorrespondence:Arkenduchatterjee

The Scope And Potential Of Vaginaldrug Delivery Kavitavermani And Sanjay Gar

A Review On Vaginal Drug Delivery Systems Krishna Sv, Ashok V And Chatterjee A* Department Of Pharmaceutics, Nalanda College Of Pharmacy Charlapally, Hyderabad Road, Nalgonda-508001, Andhra Pradesh, India

www.jpronline.inidia Corresponding Author. Bhabani Shankar Nayak, Department Of Pharmaceutics, Jeypore College Of Pharmacy,Rondapalli, Jeypore-764002, Koraput, Odisha. Novel Approaches In Vaginal Drug Delivery Systems For Local And Systemic Treatmentsbhabani Shankar Nayak *,

*,Research Article A Vaginal Drug Delivery Modelmohd. Aamir Mirza1, S. Asif3, Devinaverma Department Of Pharmaceutics

Review on Vaginal Drug Delivery Systemmanikanta Kumar. Y.S. Sgitam Institute Of Pharmacy, Gitam (Deemed To Be University), Rushikonda, Visakhapatnam-530045, Andhra Pradesh. Indo American Journal Of Pharmaceutical Research, 2018

International Journal Of Molecular Sciences Review Approaches In Polymeric Nanoparticles For Vaginal Drug Delivery: A Review Of The State Of The Art Gerardo Leyva-Góme (Ijmsr)

Drug Delivery Systems For Vaginal Infections Sandra Borges, Joana Barbosa And Paula Teixeira* Cbqf-Centro De Biotecnologia E Químicafina – Laboratórioassociado, Escola Superior De Biotecnologia, Universidade

Review The Vagina As A Route For Systemic Drug Delivery Alamdarhussain, Fakhruahsan*Department Of Pharmaceutical Sciences, School Of Pharmacy, Texas Tech University, Health Sciences Center,1300 Coulter Drive, Amarillo, Tx 79106, United States

A Review Of Current Intravaginal Drug Delivery Approaches Employed For The Prophylaxis Of Hiv/Aids And Prevention Of Sexuallytransmitted Infections Valence M. K. Ndesendo,1

East And Central African Journal Of Pharmaceutical Sciencesvol. 10 (2007) 3-Authorto Whom Correspondence May Be Addressed.Vaginaldrug Delivery Systems: A Review Of Current Status

N. Dobaria1*, R. Mashru1 And N. H. Vadia21pharmacy Department, Faculty Of Technology And Engineering, The M. S. University Of Baroda, Kalabhavan, Post Box No. 51, Vadodara, Gujarat 390 001, India.

Published
2020-12-26
How to Cite
Ankit Kumar, & Sanjeev Kumar. (2020). Intra Vaginal Drug Delivery System (Novel Drug Delivery System). International Journal for Research in Applied Sciences and Biotechnology, 7(6), 234-241. https://doi.org/10.31033/ijrasb.7.6.33